Understanding how brain activity affects memory in temporal lobe epilepsy
Determining the shared neuronal network mechanisms of focal epileptic discharges and impaired memory processing in temporal lobe epilepsy
This study is looking at how certain brain activity related to temporal lobe epilepsy affects memory, and it's for people with this type of epilepsy who want to understand why they might have memory issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11092707 on NIH RePORTER |
What this research studies
This research investigates the connection between focal epileptic discharges and memory problems in patients with temporal lobe epilepsy. By using advanced recording techniques, the study aims to identify how specific brain networks are disrupted during memory tasks. The researchers will analyze brain activity in both human patients and a mouse model to uncover the underlying mechanisms of these memory impairments. This could lead to a better understanding of how epilepsy affects cognitive functions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with temporal lobe epilepsy who experience memory difficulties.
Not a fit: Patients without temporal lobe epilepsy or those who do not experience memory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for memory impairments in patients with temporal lobe epilepsy.
How similar studies have performed: Previous studies have shown promising results in understanding the relationship between brain activity and memory, suggesting that this approach could yield valuable insights.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Ewell, Laura — University of California-Irvine
- Study coordinator: Ewell, Laura
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.