Understanding how blood vessels adapt after a stroke
Novel Cellular and Molecular Regulation of Collateral Remodeling in Ischemic Stroke
This study is looking at how some blood vessels in the brain can change and heal after a stroke, with the hope of finding new ways to help stroke patients recover better and protect their brain tissue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project ID | NIH-10642764 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which certain blood vessels in the brain can adapt and remodel after a stroke, potentially improving blood flow to affected areas. It focuses on the role of specific proteins in the blood vessel walls that may limit their ability to grow and repair. By studying these processes in a controlled environment, researchers aim to identify new therapeutic targets that could enhance recovery for stroke patients. The ultimate goal is to develop strategies that could protect brain tissue and improve functional outcomes for individuals who have experienced a stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and may benefit from improved collateral blood flow.
Not a fit: Patients who have not experienced a stroke or have other unrelated cerebrovascular conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery and protect brain function in stroke patients.
How similar studies have performed: Previous research has shown promise in targeting collateral circulation for stroke recovery, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Blacksburg, United States
- Virginia Polytechnic Inst and St Univ — Blacksburg, United States (Active)
Researchers
- Principal investigator: Theus, Michelle Lee — Virginia Polytechnic Inst and St Univ
- Study coordinator: Theus, Michelle Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.