Understanding how bacteria defend against viruses and how viruses fight back
Discovery of bacterial defense and phage counter-defense strategies
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10894215
This study is looking at how bacteria fight off viruses that try to infect them, and it’s for anyone interested in finding new ways to treat tough bacterial infections that don’t respond to antibiotics.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10894215 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between bacteria and the viruses that infect them, known as phages. By exploring the various defense mechanisms that bacteria use to protect themselves from phage attacks, as well as the strategies that phages employ to overcome these defenses, the study aims to uncover previously unknown systems in this battle. The researchers will utilize innovative high-throughput methods to identify these defense and counter-defense systems, which could lead to new therapeutic approaches for treating bacterial infections, especially those resistant to antibiotics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from bacterial infections, especially those caused by antibiotic-resistant bacteria.
Not a fit: Patients with viral infections or those not affected by bacterial infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments for bacterial infections, particularly in cases where traditional antibiotics fail.
How similar studies have performed: Other research has shown promise in using phages as therapeutic agents against bacterial infections, indicating that this approach has potential for success.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FORSBERG, KEVIN J — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: FORSBERG, KEVIN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections