Understanding how bacteria communicate and respond to signals
Computational Genomics of Signal Transduction
This study is looking at how bacteria communicate and adapt to their surroundings, which could help scientists create better drugs to fight infections, and the results will be shared publicly to help everyone learn more about these processes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11082310 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of signal transduction in bacteria, which are crucial for understanding how these pathogens communicate and adapt to their environment. By identifying the small molecules that bacteria recognize and studying the evolution of their signaling networks, the research aims to develop predictive models that can enhance drug design. The findings will be stored in public databases to benefit the scientific community and improve our understanding of similar processes in human cells.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from bacterial infections or diseases related to bacterial pathogens.
Not a fit: Patients with non-bacterial infections or those not affected by bacterial diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new drugs targeting bacterial infections and improve treatment strategies for related diseases.
How similar studies have performed: Previous research has shown success in understanding signal transduction in other organisms, suggesting that this approach could yield valuable insights into bacterial systems as well.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Jouline, Igor B. — Ohio State University
- Study coordinator: Jouline, Igor B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.