Understanding how attention affects what we see in the brain

What Mechanisms Underlie Top-Down Modulation of Human Visual Cortex?

['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10702161

This study is looking at how our focus and memory affect what we see, using brain scans to learn more about how our minds work, especially for people who might have trouble with thinking or seeing clearly.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded)
Locations1 site (LA JOLLA, UNITED STATES)
Trial IDNIH-10702161 on ClinicalTrials.gov

What this research studies

This research investigates how top-down cognitive processes, like attention and working memory, influence our perception of visual information. By using advanced neuroimaging techniques such as fMRI and EEG, the study aims to uncover the neural mechanisms that regulate what we can perceive during selective attention tasks. The findings could enhance our understanding of visual processing and cognitive function, particularly in individuals with cognitive impairments. This research combines computational modeling with empirical evidence to provide insights into brain function.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults over 21 who may experience cognitive disturbances or impairments related to attention and perception.

Not a fit: Patients with severe neurological disorders that prevent participation in cognitive tasks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing cognitive function and addressing visual perception issues in patients with cognitive impairments.

How similar studies have performed: Previous research has shown success in using neuroimaging techniques to study cognitive processes, indicating that this approach is promising and builds on established methodologies.

Where this research is happening

LA JOLLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Brain Diseases, Brain Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.