Understanding how arterial stiffness affects blood pressure management in older veterans
Official title: Load-Dependent Arterial Stiffness to Optimize Blood Pressure Management in Older Veterans (LOADED BP)
Funded at Wm S. Middleton Memorial Veterans Hosp · NIH-10912973 · Data updated 2026-11-12
This study is looking at how stiff arteries affect blood pressure in older veterans with high blood pressure, and it aims to find better ways to treat them by using simple tests and genetic information to personalize their care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| NIH project number | 1I01CX002720-01A1 |
| Project ID | NIH-10912973 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older veterans diagnosed with hypertension who may benefit from personalized blood pressure treatment approaches.
✕Less likely to help
Patients who are not veterans or those without hypertension may not receive any benefit from this research.
What this research studies
This research investigates how arterial stiffness impacts blood pressure control in older veterans, particularly focusing on those with hypertension. The study aims to identify non-invasive measures of arterial stiffness and utilize genetic information to tailor blood pressure treatment strategies. By comparing intensive versus standard blood pressure treatment targets, the research seeks to enhance the understanding of how individual differences in arterial stiffness influence treatment responses. Ultimately, the goal is to improve blood pressure management and health outcomes for older veterans.
Why it matters
Potential benefit: If successful, this research could lead to more effective blood pressure management strategies tailored to individual veterans, potentially reducing cardiovascular disease risk.
How similar studies have gone: Previous research has shown promise in using arterial stiffness measurements to improve blood pressure management, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
-
Wm S. Middleton Memorial Veterans Hosp
Madison, United States Active
Researchers
- Principal investigator: Gepner, Adam D — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Gepner, Adam D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.