Understanding how anxiety affects learning and behavior

Neurocomputational substrates of maladaptive uncertainty learning and avoidance in anxiety

['FUNDING_OTHER'] · EMORY UNIVERSITY · NIH-10989870

This study looks at how anxiety affects the way we learn to deal with uncertainty and avoid certain situations, using brain scans and computer models to understand what's happening in the brain, and it hopes to help people with anxiety by finding better ways to treat it based on real-life behaviors.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorEMORY UNIVERSITY (nih funded)
Locations1 site (ATLANTA, UNITED STATES)
Trial IDNIH-10989870 on ClinicalTrials.gov

What this research studies

This research investigates how anxiety disorders disrupt the learning processes related to uncertainty and avoidance behaviors. It employs advanced neuroimaging and computational modeling techniques to explore the neural mechanisms underlying these disruptions. Patients may benefit from insights gained through ecological momentary assessments that capture real-time behaviors in anxiety. The research aims to identify specific patterns of behavior and brain activity associated with anxiety, which could inform more effective treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with anxiety disorders who experience significant avoidance behaviors.

Not a fit: Patients with anxiety who do not exhibit avoidance behaviors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for individuals suffering from anxiety disorders.

How similar studies have performed: Previous research has shown promising results in understanding anxiety through neuroimaging and computational modeling, suggesting that this approach could yield valuable insights.

Where this research is happening

ATLANTA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anxiety Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.