NIH-funded research NIH-funded research

Understanding how anxiety affects learning and behavior

Official title: Neurocomputational substrates of maladaptive uncertainty learning and avoidance in anxiety

Funded at Emory University · NIH-10989870 · Data updated 2026-11-12

This study looks at how anxiety affects the way we learn to deal with uncertainty and avoid certain situations, using brain scans and computer models to understand what's happening in the brain, and it hopes to help people with anxiety by finding better ways to treat it based on real-life behaviors.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startFebruary 19, 2024
Project endNovember 30, 2025
Funding year2025
Award (this year)$170,777
NIH project number5K23MH122626-06
Project IDNIH-10989870 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with anxiety disorders who experience significant avoidance behaviors.

Less likely to help

Patients with anxiety who do not exhibit avoidance behaviors may not benefit from this research.

What this research studies

This research investigates how anxiety disorders disrupt the learning processes related to uncertainty and avoidance behaviors. It employs advanced neuroimaging and computational modeling techniques to explore the neural mechanisms underlying these disruptions. Patients may benefit from insights gained through ecological momentary assessments that capture real-time behaviors in anxiety. The research aims to identify specific patterns of behavior and brain activity associated with anxiety, which could inform more effective treatments.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for individuals suffering from anxiety disorders.

How similar studies have gone: Previous research has shown promising results in understanding anxiety through neuroimaging and computational modeling, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Brown, Vanessa — Emory University
  • Study coordinator: Brown, Vanessa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.