NIH-funded research R21 grant

Understanding how aging affects navigation skills.

Official title: A neurocomputational model of age-related differences in navigation.

Funded at University of Arizona · NIH-10840971 · Data updated 2026-11-12

This study is looking at how getting older affects the way people find their way around, especially for older adults and those with mild cognitive issues, by using virtual reality to see how they use different clues to navigate new places.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startMay 15, 2023
Project endJanuary 31, 2026
Funding year2024
Award (this year)$230,250
NIH project number5R21AG081558-02
Project IDNIH-10840971 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include older adults, particularly those experiencing mild cognitive impairment or early signs of Alzheimer's disease.

Less likely to help

Patients who are younger than 21 years old or those without cognitive impairments may not benefit from this research.

What this research studies

This research investigates how age-related changes impact navigation abilities, particularly in older adults and those with mild cognitive impairment, a precursor to Alzheimer's disease. By developing a neurocomputational model, the study aims to explore how older individuals rely on different types of cues when navigating unfamiliar environments. Participants will engage in immersive virtual reality experiences to assess their navigation strategies and cognitive processes. The findings could lead to a better understanding of the cognitive challenges faced by older adults in navigation.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cognitive decline in aging, potentially leading to improved interventions for navigation difficulties in older adults.

How similar studies have gone: Previous research has shown promise in using computational models to understand cognitive processes, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Ekstrom, Arne D — University of Arizona
  • Study coordinator: Ekstrom, Arne D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.