NIH-funded research R01 grant

Understanding how aging affects emotional regulation

Official title: Neural and motivational mechanisms of age-related change in emotion regulation

Funded at Washington University · NIH-11259819 · Data updated 2026-11-12

This study is looking at how our emotions change as we get older, especially for those over 65, and it wants to understand what helps older adults feel happier and how past experiences with depression might play a role.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startApril 15, 2021
Project endJanuary 31, 2026
Funding year2025
Award (this year)$348,746
NIH project number3R01AG070139-05S1
Project IDNIH-11259819 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are healthy adults aged 65 and older, especially those with varying histories of depression.

Less likely to help

Patients under 65 years of age or those with severe cognitive impairments may not benefit from this research.

What this research studies

This research investigates how emotional functioning changes as people age, particularly focusing on individuals over 65. It aims to identify the factors that contribute to positive emotional development in older adults and how a history of depression may influence these changes. The study employs a framework that examines the relationship between motivation and cognitive control in managing emotions, specifically looking at how these elements interact in older adults. By analyzing brain activity and connectivity, the research seeks to uncover the mechanisms behind emotional regulation in aging.

Why it matters

Potential benefit: If successful, this research could enhance emotional well-being and coping strategies for older adults, particularly those with a history of depression.

How similar studies have gone: Previous research has shown promising results in understanding emotional regulation in aging, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: English, Tammy — Washington University
  • Study coordinator: English, Tammy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.