Understanding how aging affects emotional regulation

Neural and motivational mechanisms of age-related change in emotion regulation

NIH-funded research Washington University · NIH-11259819

This study is looking at how our emotions change as we get older, especially for those over 65, and it wants to understand what helps older adults feel happier and how past experiences with depression might play a role.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11259819 on NIH RePORTER

What this research studies

This research investigates how emotional functioning changes as people age, particularly focusing on individuals over 65. It aims to identify the factors that contribute to positive emotional development in older adults and how a history of depression may influence these changes. The study employs a framework that examines the relationship between motivation and cognitive control in managing emotions, specifically looking at how these elements interact in older adults. By analyzing brain activity and connectivity, the research seeks to uncover the mechanisms behind emotional regulation in aging.

Who could benefit from this research

Good fit: Ideal candidates for this research are healthy adults aged 65 and older, especially those with varying histories of depression.

Not a fit: Patients under 65 years of age or those with severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance emotional well-being and coping strategies for older adults, particularly those with a history of depression.

How similar studies have performed: Previous research has shown promising results in understanding emotional regulation in aging, suggesting that this approach could yield valuable insights.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.