Understanding how a specific protein affects eye growth and vision errors
Characterizing the Molecular Mechanisms of PRSS56-Dependent Ocular Growth and Refractive Error
This study is looking at how a protein called PRSS56 affects eye growth and vision problems like myopia, with the hope of finding new ways to help people with these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10880614 on NIH RePORTER |
What this research studies
This research investigates the molecular and genetic mechanisms that regulate eye growth and refractive errors, particularly focusing on a protein called PRSS56. By studying how this protein influences the growth of the eye during both prenatal and postnatal development, the research aims to uncover the processes that lead to conditions like myopia. The approach involves examining the signals between the retina and the sclera that contribute to proper eye development and refractive accuracy. Patients may benefit from insights that could lead to new treatments for vision problems caused by improper eye growth.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing refractive errors, particularly those with myopia or related vision issues.
Not a fit: Patients with refractive errors not related to the mechanisms being studied, or those with other unrelated ocular conditions, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating refractive errors like myopia, potentially reducing the risk of vision loss.
How similar studies have performed: Previous research has shown promise in understanding the genetic factors influencing eye growth, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Nair, Kayarat Saidas — University of California, San Francisco
- Study coordinator: Nair, Kayarat Saidas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.