Understanding how a specific brain area affects attention

Investigation of Locus Coeruleus Function in Sustained Attention

NIH-funded research University of California at Davis · NIH-10693968

This study is looking at a tiny part of the brain that helps control attention and thinking, and it's inviting people with ADHD or schizophrenia to take part in brain scans and attention tasks to learn more about how this area affects their daily lives.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10693968 on NIH RePORTER

What this research studies

This research investigates the role of the locus coeruleus, a small brain structure, in regulating attention and cognitive functions. By developing new methods to measure its activity using advanced imaging techniques, the study aims to better understand how this area influences mental health disorders like ADHD and schizophrenia. Patients may participate in assessments that involve brain imaging and attention tasks to help validate these new measurement techniques. The ultimate goal is to improve our understanding of attention-related issues and their impact on daily life.

Who could benefit from this research

Good fit: Ideal candidates include individuals diagnosed with attention-related disorders such as ADHD or schizophrenia.

Not a fit: Patients without attention-related disorders or those who do not experience cognitive challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for attention-related mental health disorders.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study brain function, but this specific approach to measuring locus coeruleus activity is novel.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.