Understanding how a new protein affects fat metabolism in the liver
Regulation of hepatic lipid metabolism by novel protein BASIC
This study is looking at a new protein called BASIC to see how it affects fat storage in the liver and body, which could help find new treatments for non-alcoholic fatty liver disease (NAFLD) and improve health for those dealing with it.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10857165 on NIH RePORTER |
What this research studies
This research investigates the role of a novel protein called BASIC in regulating lipid metabolism, particularly in the context of non-alcoholic fatty liver disease (NAFLD). The study focuses on how BASIC influences the size and function of lipid droplets in liver and adipose tissues, which are crucial for managing fat storage and utilization. By examining the interactions of BASIC with other proteins involved in lipid metabolism, the research aims to uncover new therapeutic targets for treating NAFLD and its associated complications. Patients may benefit from insights that could lead to innovative treatments for liver-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults suffering from non-alcoholic fatty liver disease, particularly those with obesity or insulin resistance.
Not a fit: Patients with liver diseases unrelated to fat metabolism or those who do not have non-alcoholic fatty liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for non-alcoholic fatty liver disease, potentially reducing the risk of severe liver conditions.
How similar studies have performed: Previous research has shown promising results in understanding lipid metabolism and its implications for liver health, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Uchiyama, Lauren F — University of California Los Angeles
- Study coordinator: Uchiyama, Lauren F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.