Understanding heart health risks after preeclampsia
Stress, inflammation and coronary endothelial injury in preeclampsia
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11121893
This work explores how stress and inflammation during preeclampsia might lead to heart problems later in life for women.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11121893 on ClinicalTrials.gov |
What this research studies
Preeclampsia, a high blood pressure condition during pregnancy, significantly increases a woman's risk of heart disease years later. This project aims to understand the biological and social factors, like stress and inflammation, that connect preeclampsia to future heart issues. We want to learn how preeclampsia affects blood vessels and the heart, considering both physical changes and social influences. The goal is to identify new ways to prevent heart disease in young women who have experienced preeclampsia.
Who could benefit from this research
Good fit: This work is relevant for women who have experienced preeclampsia and are concerned about their long-term heart health.
Not a fit: Patients without a history of preeclampsia or related cardiovascular concerns may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better ways to identify women at high risk for heart disease after preeclampsia and develop new treatments to protect their heart health.
How similar studies have performed: While the link between preeclampsia and later heart disease is known, this project explores specific biological and socio-behavioral mechanisms, which is an area of ongoing and evolving research.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAYS, ALLISON G — JOHNS HOPKINS UNIVERSITY
- Study coordinator: HAYS, ALLISON G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus, Atherosclerotic Cardiovascular Disease, Blood Diseases