Understanding Heart, Blood Vessel, and Lupus Conditions
CORE C- Protein Expression and Purification
['FUNDING_P01'] · CLEVELAND CLINIC LERNER COM-CWRU · NIH-11124002
This core facility helps researchers understand heart and blood vessel diseases, and lupus, by providing specialized animal models and tissue analysis.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEVELAND CLINIC LERNER COM-CWRU (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11124002 on ClinicalTrials.gov |
What this research studies
This core facility supports larger research projects focused on conditions like atherosclerosis (hardening of arteries), blood clots, and lupus. It provides researchers with specialized animal models to study these diseases and offers comprehensive analysis of tissue, blood, and urine samples. This helps individual research teams avoid setting up these complex techniques themselves, making the overall research more efficient and consistent. The core also has access to archived human tissue samples, ensuring ethical use for further analysis. This collaborative approach aims to speed up discoveries in these important disease areas.
Who could benefit from this research
Good fit: This grant funds a core facility, so it does not directly recruit patients, but future studies supported by this core may seek patients with atherosclerotic cardiovascular disease, arterial thrombosis, venous thrombosis, or lupus.
Not a fit: Patients not affected by atherosclerotic cardiovascular disease, blood clots, or lupus would not directly benefit from the research supported by this core.
Why it matters
Potential benefit: If successful, this core facility will accelerate discoveries in heart disease, blood clots, and lupus, potentially leading to new treatments.
How similar studies have performed: Core facilities like this are a standard and successful way to support complex biomedical research by centralizing specialized services.
Where this research is happening
CLEVELAND, UNITED STATES
- CLEVELAND CLINIC LERNER COM-CWRU — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, YUNMEI — CLEVELAND CLINIC LERNER COM-CWRU
- Study coordinator: WANG, YUNMEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease