Understanding genetic factors in obsessive-compulsive disorder in Latin Americans
Official title: 2/2 TRANS-ANCESTRY GENOMIC ANALYSIS OF OBSESSIVE COMPULSIVE DISORDER
Funded at Baylor College of Medicine · NIH-10851757 · Data updated 2026-11-12
This study is looking at how genes might influence the risk of developing obsessive-compulsive disorder (OCD) in people from Latin America, and it's for anyone with OCD who wants to help us learn more about the condition to improve future treatments and support.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 17, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $537,483 |
| NIH project number | 5U01MH125062-04 |
| Project ID | NIH-10851757 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with obsessive-compulsive disorder from Latin American backgrounds.
✕Less likely to help
Patients who do not have obsessive-compulsive disorder or are not of Latin American descent may not benefit from this research.
What this research studies
This research investigates how genetic factors contribute to the risk of developing obsessive-compulsive disorder (OCD) among individuals in Latin America. By collecting a diverse sample of 5,000 OCD cases from various clinics across Latin America and the USA, the study aims to enhance our understanding of the genetic architecture of OCD. Participants will undergo detailed clinical assessments, including evaluations of comorbidities and OCD symptom dimensions. The findings could lead to improved detection, treatment, and prevention strategies for OCD based on genetic insights.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and prevention strategies for obsessive-compulsive disorder tailored to the genetic backgrounds of patients.
How similar studies have gone: Previous research in other psychiatric disorders has shown success in using genomic analysis to uncover genetic factors, suggesting a promising approach for OCD as well.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Storch, Eric a. — Baylor College of Medicine
- Study coordinator: Storch, Eric a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.