Understanding gene regulation in cardiovascular disease
BLRD Research Career Scientist Award Renewal
This study is looking at how certain genes affect heart and blood vessel health, especially in veterans, to find new ways to prevent and treat heart problems like atherosclerosis and vascular calcification.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10948890 on NIH RePORTER |
What this research studies
This research focuses on the mechanisms of gene regulation that contribute to cardiovascular disease, particularly among veterans. The team investigates how vascular smooth muscle cells change and how these changes lead to conditions like atherosclerosis and vascular calcification. By using advanced animal models, they aim to identify new molecular targets for prevention and treatment strategies. The findings could help develop innovative therapies to improve cardiovascular health.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans and individuals at risk for cardiovascular diseases, particularly those with conditions like diabetes or atherosclerosis.
Not a fit: Patients with non-cardiovascular diseases or those not at risk for cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent or mitigate cardiovascular diseases in patients.
How similar studies have performed: Previous research has shown promising results in understanding gene regulation in cardiovascular diseases, indicating that this approach has potential for success.
Where this research is happening
Portland, United States
- Portland VA Medical Center — Portland, United States (Active)
Researchers
- Principal investigator: Chen, Yabing — Portland VA Medical Center
- Study coordinator: Chen, Yabing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.