Understanding frailty in lung transplant patients
Official title: Molecular phenotypes of frailty in lung transplantation
Funded at University of California, San Francisco · NIH-10918576 · Data updated 2026-11-12
This study looks at how things like aging and body health can impact the recovery and well-being of people getting lung transplants, with the goal of finding ways to improve care and support for these patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $126,099 |
| NIH project number | 1K24HL174231-01 |
| Project ID | NIH-10918576 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are being considered for lung transplantation.
✕Less likely to help
Patients who are younger than 65 or those who do not require lung transplantation may not benefit from this research.
What this research studies
This research investigates how factors related to aging, such as frailty and body composition, affect the health outcomes of patients before and after lung transplantation. By analyzing these molecular phenotypes, the study aims to identify risk factors that contribute to complications and overall quality of life for lung transplant recipients. The approach includes multicenter collaborations and a focus on patient-centered outcomes, which may lead to improved guidelines for lung transplant candidacy and care.
Why it matters
Potential benefit: If successful, this research could lead to better assessment and management strategies for lung transplant candidates, ultimately improving their health outcomes.
How similar studies have gone: Previous research has shown that understanding frailty and related factors can significantly impact patient outcomes in transplant settings, indicating a promising avenue for further exploration.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Singer, Jonathan Paul — University of California, San Francisco
- Study coordinator: Singer, Jonathan Paul
Related research
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-
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-
Body composition and outcomes after lung transplant
A patient-focused look at how body fat and muscle measurements around the time of lung transplant relate to recovery, complications, and quality of life after surgery.
-
Exercise-based frailty program for people awaiting lung transplants
A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.
-
AI-enabled bone aging and frailty markers in osteoporosis using advanced imaging
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.