Understanding fatigue in health and after COVID-19
Neurobiological Mechanisms of Fatigue in Health and after COVID-19
This study is looking at how fatigue affects people recovering from COVID-19, trying to understand what makes them feel tired and how hard they’re willing to work, so we can find better ways to help those who are struggling with this issue.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10872162 on NIH RePORTER |
What this research studies
This research investigates the neurobiological mechanisms behind fatigue, particularly in individuals recovering from COVID-19. It aims to explore how fatigue manifests in terms of weariness, perceived effort, and willingness to exert effort. By employing innovative neuromuscular and computational methods, the study seeks to objectively measure these aspects of fatigue in both healthy individuals and those experiencing post-acute sequelae of SARS-CoV-2 infection (PASC). The findings could lead to better understanding and treatment options for fatigue, which is often debilitating and poorly managed.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing severe fatigue after COVID-19 as well as healthy individuals for comparative analysis.
Not a fit: Patients who do not experience fatigue or those with acute COVID-19 symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for diagnosing and treating fatigue in patients, especially those recovering from COVID-19.
How similar studies have performed: Previous research has shown promise in understanding fatigue through various neurobiological approaches, but this specific investigation into PASC-related fatigue is relatively novel.
Where this research is happening
Baltimore, United States
- Hugo W. Moser Res Inst Kennedy Krieger — Baltimore, United States (Active)
Researchers
- Principal investigator: Casamento Moran, Agostina — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Casamento Moran, Agostina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.