Understanding family factors and costs affecting treatment for opioid use disorder
Official title: Real-world complexities in opioid use disorder treatment: understanding family comorbidity, high-risk medication use, and costs related to treatment adherence and health outcomes
Funded at University of California Los Angeles · NIH-11059105 · Data updated 2026-11-12
This study is looking at how family issues and other health problems can make it harder for people with opioid use disorder to stick to their treatment, so we can help doctors find those who might need extra support.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | April 1, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $193,925 |
| NIH project number | 5K01DA054359-04 |
| Project ID | NIH-11059105 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with opioid use disorder, particularly those who have family members with co-occurring mental health or substance use disorders.
✕Less likely to help
Patients without opioid use disorder or those who do not have family members with relevant comorbidities may not benefit from this research.
What this research studies
This research investigates the challenges faced by individuals with opioid use disorder (OUD) in adhering to treatment, particularly focusing on the role of family comorbidities and high-risk medication use. By examining how mental health issues, pain, and substance use disorders co-occur within families, the study aims to identify patients who may struggle with treatment adherence. The research will also analyze the financial implications of non-adherence to buprenorphine treatment, which is crucial for informing health insurance policies. Ultimately, the goal is to develop a prediction model that helps healthcare providers identify patients at risk for inadequate treatment adherence.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment adherence for patients with opioid use disorder, enhancing their health outcomes and overall well-being.
How similar studies have gone: Previous research has shown that understanding family dynamics and comorbidities can significantly impact treatment outcomes in substance use disorders, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Seamans, Marissa J — University of California Los Angeles
- Study coordinator: Seamans, Marissa J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.