Understanding early signs of autoimmune diseases like Sjögren's and lupus
Official title: Early-Stage Autoimmunity in Sjögren's Disease and Systemic Lupus Erythematosus
Funded at University of Oklahoma Hlth Sciences Ctr · NIH-10998323 · Data updated 2026-11-12
This study is looking at people who have early signs of autoimmune diseases like Sjögren's and lupus to find helpful markers that can lead to quicker diagnoses and better treatments before the diseases fully develop.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $36,806 |
| NIH project number | 1F31DE034904-01 |
| Project ID | NIH-10998323 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals showing early symptoms of Sjögren's disease or systemic lupus erythematosus, along with positive serological tests but who do not yet meet the full criteria for diagnosis.
✕Less likely to help
Patients who have already been diagnosed with advanced stages of Sjögren's disease or systemic lupus erythematosus may not benefit from this research.
What this research studies
This research investigates the early stages of autoimmune diseases, specifically Sjögren's disease and systemic lupus erythematosus, by focusing on patients who show early symptoms and positive serology but do not yet meet full diagnostic criteria. The study aims to identify biomarkers that can help in early diagnosis and predict disease progression, which could lead to better-targeted therapies. By examining these early stages, the research seeks to uncover the molecular mechanisms behind these diseases without the confounding effects of long-term treatment or disease damage.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more effective treatment options for patients with autoimmune diseases.
How similar studies have gone: Previous research has shown promise in understanding early autoimmune disease mechanisms, but this specific approach focusing on non-classified patients is relatively novel.
Where this research is happening
-
University of Oklahoma Hlth Sciences Ctr
Oklahoma City, United States Active
Researchers
- Principal investigator: Wood, Rebecca Aden — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Wood, Rebecca Aden
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.