Understanding different types of type 2 diabetes in diverse populations
Official title: Metabolomic and genomic expansion of type 2 diabetes subtyping in multiethnic populations
Funded at Wake Forest University Health Sciences · NIH-10975140 · Data updated 2026-11-12
This study is looking at how type 2 diabetes can be different for people from various backgrounds by exploring genetic and metabolic factors, so we can find better ways to treat and manage the condition for everyone.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $643,058 |
| NIH project number | 1U01DK140778-01 |
| Project ID | NIH-10975140 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with type 2 diabetes, particularly those from diverse racial and ethnic backgrounds.
✕Less likely to help
Patients who do not have type 2 diabetes or those outside the age range of 21 years and older may not benefit from this research.
What this research studies
This research aims to identify and classify different subtypes of type 2 diabetes (T2D) by examining genetic and metabolic factors across various ethnic groups. By analyzing data from multiple studies, the project seeks to understand how T2D manifests differently in individuals, which can help tailor treatment strategies to improve patient outcomes. The research will focus on integrating diverse data types to uncover the physiological drivers behind T2D complications and responses to treatment. Ultimately, this work aims to enhance clinical decision-making for managing T2D.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for individuals with type 2 diabetes.
How similar studies have gone: Previous research has shown promise in subclassifying type 2 diabetes, but this study aims to expand on those findings by including a more diverse population, making it a novel approach.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Bancks, Michael Patrick — Wake Forest University Health Sciences
- Study coordinator: Bancks, Michael Patrick
Related research
Other NIH-funded projects on the same topics.
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Subtyping Core for Research on the Causes of Type 2 Diabetes (SCORE-T2D)
A new U01 grant from a university research team aims to understand why Type 2 diabetes differs so much between people and how to tailor prevention and treatment.
-
Michigan Diabetes Project: A Peer-Led Self-Management Program for Adults with Type 2 Diabetes
A peer-led self-management program for adults with type 2 diabetes is being tested to see if it improves blood sugar control and daily diabetes care.
-
Alzheimer’s and dementia risk in people with prediabetes or type 2 diabetes
This grant aims to understand why some older adults with prediabetes or type 2 diabetes develop memory problems or dementia.
-
Personalized use of newer diabetes medicines for Type 2 diabetes
Aiming to tailor use of newer glucose-lowering drugs for people with type 2 diabetes to improve health and access in real-world settings.
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Alzheimer’s and related dementia in older adults with prediabetes or type 2 diabetes
This grant aims to understand why cognitive problems occur in people 65 and older who have prediabetes or type 2 diabetes, using data from a long-running diabetes study to identify what drives memory and thinking decline.
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Understanding why youth develop type 2 diabetes and how to prevent it
A nationwide study aims to unravel why some teens with obesity develop type 2 diabetes while others don’t, and to identify factors that could help prevent it.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.