Understanding different types of type 2 diabetes in diverse populations

Metabolomic and genomic expansion of type 2 diabetes subtyping in multiethnic populations

NIH-funded research Wake Forest University Health Sciences · NIH-10975140

This study is looking at how type 2 diabetes can be different for people from various backgrounds by exploring genetic and metabolic factors, so we can find better ways to treat and manage the condition for everyone.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-10975140 on NIH RePORTER

What this research studies

This research aims to identify and classify different subtypes of type 2 diabetes (T2D) by examining genetic and metabolic factors across various ethnic groups. By analyzing data from multiple studies, the project seeks to understand how T2D manifests differently in individuals, which can help tailor treatment strategies to improve patient outcomes. The research will focus on integrating diverse data types to uncover the physiological drivers behind T2D complications and responses to treatment. Ultimately, this work aims to enhance clinical decision-making for managing T2D.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with type 2 diabetes, particularly those from diverse racial and ethnic backgrounds.

Not a fit: Patients who do not have type 2 diabetes or those outside the age range of 21 years and older may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for individuals with type 2 diabetes.

How similar studies have performed: Previous research has shown promise in subclassifying type 2 diabetes, but this study aims to expand on those findings by including a more diverse population, making it a novel approach.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusAtherosclerotic Cardiovascular Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.