Understanding Diabetes Risk in People Living with HIV
Understanding the Mechanism of HIV Associated with Diabetic Complications in Low- and Middle-Income Country
This project explores why people living with HIV might develop diabetes, focusing on how their immune cells and certain cellular stress contribute to this risk.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11142525 on NIH RePORTER |
What this research studies
We are looking into how specific immune cells, called NK cells, might harm the pancreas and lead to diabetes in people with HIV. We also want to understand if stress inside the body's cells, caused by HIV or its treatments, makes the pancreas more vulnerable. Our goal is to find ways to reduce this risk, possibly using affordable medications that can lessen cell stress. This work builds on our previous findings about immune changes in people with HIV and their link to other health issues.
Who could benefit from this research
Good fit: This research is relevant for adults aged 21 and older who are living with HIV and are at risk for or have developed diabetic complications.
Not a fit: Patients who do not have HIV or diabetes, or are not at risk for these conditions, may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to prevent or manage diabetes in people living with HIV, potentially through low-cost treatments.
How similar studies have performed: This project builds upon previous research findings and existing literature that have identified altered immune responses and increased diabetes risk in people living with HIV.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Liyanage, Namal — Ohio State University
- Study coordinator: Liyanage, Namal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.