Understanding cryptosporidiosis in young children in Bangladesh
Official title: Field Studies of Cryptosporidiosis in Bangladesh
Funded at University of Virginia · NIH-11527423 · Data updated 2026-11-12
A study in Bangladesh aims to learn how immunity and genes in children and the parasite influence who gets infected with cryptosporidiosis and how sick they become.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | September 15, 1998 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $87,346 |
| NIH project number | 3R01AI043596-27S1 |
| Project ID | NIH-11527423 on NIH RePORTER |
Who could benefit from this research
✓Could help
Young children in high-risk settings, particularly infants in Dhaka, Bangladesh, and other populations where cryptosporidiosis is common.
✕Less likely to help
Children in areas with low exposure or different disease dynamics may not directly benefit.
What this research studies
This project follows a birth cohort of infants in a high-transmission area of Dhaka to track Cryptosporidium infections over time. It will examine how acquired immunity develops and how human and parasite genes affect susceptibility and disease severity. The findings could inform future prevention and treatment strategies for diarrheal illness in vulnerable children. The work will connect international field research with US-based public health relevance, focusing on child health and growth in food-insecure settings.
Why it matters
Potential benefit: If successful, the study could lead to new ways to prevent or reduce diarrhea and growth faltering in young children.
How similar studies have gone: Previous work has shown that immunity and genetics influence susceptibility to cryptosporidiosis, though the specific correlates are not fully defined.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Petri, William a — University of Virginia
- Study coordinator: Petri, William a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.