Understanding Childhood Liver Diseases at Seattle Children's
Continuation of the Childhood Liver Disease Research Network - Seattle Clinical Center
This effort gathers important information and samples from children with rare liver conditions to help us learn more about these diseases.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11124803 on NIH RePORTER |
What this research studies
This project continues to collect valuable health information and biological samples from children facing rare liver diseases like biliary atresia and primary sclerosing cholangitis. By bringing together data from many children, including those from diverse backgrounds like Alaska Natives and Native Hawaiians, we hope to better understand how these conditions develop. This long-term effort helps track how these diseases progress over time and how different treatments work. Our goal is to find better ways to manage these serious liver conditions in children.
Who could benefit from this research
Good fit: Ideal participants are children, typically 0-11 years old, diagnosed with conditions such as biliary atresia, Alagille Syndrome, or primary sclerosing cholangitis.
Not a fit: Patients without childhood cholestatic liver diseases or those outside the specified age range would not directly benefit from participation in this specific data collection.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of childhood liver diseases, helping doctors develop more effective management strategies and treatments for affected children.
How similar studies have performed: This project builds upon successful prior phases of the Childhood Liver Disease Research Network, which has already created extensive collections of data and biological specimens.
Where this research is happening
Seattle, United States
- Seattle Children's Hospital — Seattle, United States (Active)
Researchers
- Principal investigator: Valentino, Pamela — Seattle Children's Hospital
- Study coordinator: Valentino, Pamela
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.