Understanding Childhood Cholestatic Liver Diseases
BCM/TCH Cholestatic Liver Disease Consortium
['FUNDING_U01'] · BAYLOR COLLEGE OF MEDICINE · NIH-11129821
This research brings together experts to better understand and improve care for children with serious liver conditions like Alagille syndrome.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11129821 on ClinicalTrials.gov |
What this research studies
Many severe liver diseases in children, such as Alagille syndrome and alpha-1 antitrypsin deficiency, can lead to serious health problems and often require a liver transplant. Because no single hospital sees enough children with these rare conditions, this project brings together a network of specialists. Our goal is to learn more about what causes these diseases, how to diagnose them best, and the most effective ways to treat them. We also want to understand what makes these diseases more or less severe over time.
Who could benefit from this research
Good fit: Children with cholestatic liver diseases, including Alagille syndrome, alpha-1 antitrypsin deficiency, biliary atresia, and other related conditions, are the focus of this research.
Not a fit: Patients with liver conditions not related to cholestatic liver diseases or those outside of childhood may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to improved diagnosis, better treatments, and a deeper understanding of childhood cholestatic liver diseases, potentially reducing the need for liver transplantation.
How similar studies have performed: This project is a continuation of ongoing, successful research within the Childhood Liver Disease Research Network (ChiLDReN), building on exemplary performance to date.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHNEIDER, BENJAMIN L — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: SHNEIDER, BENJAMIN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alagille Syndrome, Alagille-Watson Syndrome