Understanding brain patterns in anxiety disorders and their comorbidities
Official title: HARM-A: A neurobiological predictor of comorbidity and stress reactivity in anxiety disorders
Funded at Texas A&m University · NIH-11052460 · Data updated 2026-11-12
This study is looking at how certain brain patterns might help us understand and predict the severity of multiple anxiety disorders in people, so we can find better ways to treat those who are dealing with more than one type of anxiety.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project start | May 15, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $515,690 |
| NIH project number | 5R01MH125083-05 |
| Project ID | NIH-11052460 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with anxiety disorders who also experience comorbid conditions.
✕Less likely to help
Patients with anxiety disorders who do not have any comorbid conditions may not benefit from this research.
What this research studies
This research investigates how specific brain patterns relate to the presence of multiple anxiety disorders in individuals. By examining the amygdala's heightened activity and reduced attention to negative stimuli, the study aims to identify a neural profile that could predict the severity of anxiety comorbidities. Patients will undergo brain imaging and EEG assessments to explore these connections, which may help clinicians better understand and treat complex anxiety cases.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with multiple anxiety disorders, enhancing their overall mental health outcomes.
How similar studies have gone: Previous research has shown promising results in understanding brain connectivity in anxiety disorders, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Texas A&m University
College Station, United States Active
Researchers
- Principal investigator: Macnamara, Annmarie Eileen — Texas A&m University
- Study coordinator: Macnamara, Annmarie Eileen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.