Understanding brain differences in schizophrenia and related conditions

Neuroimaging Dimensions at the Extremes of the Schizophrenia Spectrum

NIH-funded research University of California-Irvine · NIH-10928778

This study is looking at how schizophrenia affects the brain and how things like medication and how long someone has had the condition can change what we see in brain scans, all to help find better ways to identify and treat people with schizophrenia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10928778 on NIH RePORTER

What this research studies

This research investigates the neurobiological underpinnings of schizophrenia, a severe mental health disorder, by utilizing advanced neuroimaging techniques. The study aims to identify brain abnormalities associated with schizophrenia and how factors like medication and disease duration affect these findings. By analyzing data from large-scale collaborative efforts, the research seeks to improve early identification and treatment strategies for individuals affected by this condition. Patients may undergo brain imaging to help researchers understand the relationship between brain structure and schizophrenia symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with schizophrenia or those exhibiting subclinical psychotic traits.

Not a fit: Patients with other mental health disorders unrelated to schizophrenia may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods and more effective treatments for schizophrenia, enhancing patient outcomes.

How similar studies have performed: Previous research has shown promising results in understanding brain abnormalities in schizophrenia through neuroimaging, indicating that this approach has potential for significant insights.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brain DiseasesBrain Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.