Understanding brain connections in depression and anxiety

Multidimensional brain connectome features of depression and anxiety

['FUNDING_CAREER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11000757

This study is looking at how different parts of the brain talk to each other in people with depression and anxiety, using special MRI technology to create detailed maps, so we can better understand these conditions and find new ways to help.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11000757 on ClinicalTrials.gov

What this research studies

This research investigates how different regions of the brain communicate with each other in individuals suffering from depression and anxiety. By using advanced 7-Tesla MRI technology, the study aims to create detailed maps of brain connectivity, focusing on specific areas involved in emotion regulation. The researchers will compare these brain maps between healthy individuals and those diagnosed with major depressive disorder and generalized anxiety disorder. The goal is to identify unique brain network patterns that could serve as biomarkers for these conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with major depressive disorder or generalized anxiety disorder.

Not a fit: Patients with other mental health conditions not related to depression or anxiety may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted treatments for depression and anxiety.

How similar studies have performed: Previous research has shown promise in using advanced brain imaging techniques to understand mood and anxiety disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Affective Disorders, Anxiety Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.