Understanding brain circuits that influence eating behavior

Elucidating MCH neural circuitry underlying consummatory behavior

NIH-funded research University of Michigan at Ann Arbor · NIH-11083103

This study is looking at how specific brain cells influence our cravings and eating choices, even when we're not hungry, to help us better understand and treat obesity and eating disorders.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11083103 on NIH RePORTER

What this research studies

This research investigates the neural circuits involved in eating behaviors, particularly focusing on how certain brain cells, known as melanin-concentrating hormone (MCH) neurons, affect our cravings and decisions to eat. By examining both the biological and psychological factors that drive consumption, the study aims to uncover the complex motivations behind eating, including those that occur even when we are not hungry. The approach involves advanced techniques to map and analyze the brain's circuitry related to appetite regulation and reward. This could lead to new insights into treating obesity and eating disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals struggling with obesity or eating disorders who are interested in understanding the underlying neural mechanisms of their conditions.

Not a fit: Patients who do not have issues related to eating behaviors or weight management may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to innovative treatments for obesity and eating disorders by targeting the brain circuits that influence eating behavior.

How similar studies have performed: Previous research has shown promise in understanding neural circuits related to appetite and reward, suggesting that this approach could yield valuable insights.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.