Understanding brain circuits related to mental health disorders

Revealing functional networks and circuits of the posteromedial cortex withanatomical connectivity

['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10875048

This study is exploring a part of the brain that’s connected to mental health issues like depression and anxiety, using advanced imaging in monkeys to see how it connects with other brain areas, which could help us better understand these conditions and improve treatments for people who struggle with them.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBAYLOR COLLEGE OF MEDICINE (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-10875048 on ClinicalTrials.gov

What this research studies

This research investigates the posteromedial cortex, a brain region linked to various psychiatric conditions such as depression and anxiety. By using advanced imaging techniques and tract-tracing in nonhuman primates, the study aims to map the anatomical connections of this area and understand its role in mental health. The findings could help identify how different segments of the posteromedial cortex interact with other brain networks, providing insights into the biological underpinnings of mental disorders. Ultimately, this research seeks to improve our understanding of psychiatric diseases and inform future treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing psychiatric disorders such as depression, anxiety, or schizophrenia.

Not a fit: Patients with purely physical health issues or those not experiencing any mental health disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better-targeted therapies for mental health disorders by revealing critical brain circuits involved in these conditions.

How similar studies have performed: Previous research has shown promise in mapping brain circuits related to mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.