Understanding Brain Changes in Schizophrenia and Related Conditions
Neuroimaging Dimensions at the Extremes of the Schizophrenia Spectrum
This project aims to better understand brain differences in people with schizophrenia and those with related traits, hoping to improve early detection and treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11111338 on NIH RePORTER |
What this research studies
Researchers are looking closely at brain scans from many individuals to find patterns related to schizophrenia and similar conditions. They want to see how brain structure might differ in people with schizophrenia compared to those who have some symptoms but are otherwise healthy. By comparing these groups, the team hopes to uncover key biological markers that could help identify schizophrenia earlier. This work also considers how factors like medication or how long someone has had the condition might affect brain changes.
Who could benefit from this research
Good fit: This work focuses on understanding brain changes in adults and adolescents with schizophrenia, as well as healthy individuals who experience some psychotic-like traits.
Not a fit: Patients not interested in contributing to foundational knowledge about brain disorders may not directly benefit from this specific data analysis project.
Why it matters
Potential benefit: If successful, this work could lead to new ways to identify schizophrenia earlier and develop more effective treatments with fewer side effects.
How similar studies have performed: Previous collaborative efforts have successfully identified brain differences in schizophrenia and related conditions, providing a strong foundation for this deeper investigation.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Van Erp, Theodorus G.m. — University of California-Irvine
- Study coordinator: Van Erp, Theodorus G.m.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.