Understanding brain activity related to movement and Parkinson's disease through voltage imaging
Voltage Imaging Analysis of Striatal Network Dynamics Related to Movement, Parkinson's Disease and Deep Brain Stimulation
This study is looking at how a treatment called deep brain stimulation can help improve movement and symptoms for people with Parkinson's disease by exploring how it changes brain activity in areas that control movement.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10986030 on NIH RePORTER |
What this research studies
This research investigates how electrical stimulation of the brain, known as deep brain stimulation (DBS), affects movement and symptoms of Parkinson's disease. By using advanced voltage imaging techniques, the study aims to analyze the dynamics of brain networks involved in movement control. The researchers will focus on specific brain regions, particularly the basal ganglia, to understand how abnormal brain activity patterns relate to Parkinson's disease and how DBS can modify these patterns for therapeutic benefits. Patients with Parkinson's disease may have the opportunity to contribute to this research by providing data through their DBS treatment.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with Parkinson's disease who are undergoing deep brain stimulation treatment.
Not a fit: Patients with Parkinson's disease who are not candidates for deep brain stimulation or those with other neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved DBS techniques that better manage Parkinson's disease symptoms and enhance patients' quality of life.
How similar studies have performed: Previous studies have shown promise in using similar approaches to understand brain dynamics and improve treatments for movement disorders, indicating a potential for success in this research.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Han, Xue — Boston University (Charles River Campus)
- Study coordinator: Han, Xue
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.