Understanding brain activity related to movement and Parkinson's disease through voltage imaging.
Voltage Imaging Analysis of Striatal Network Dynamics Related to Movement, Parkinson's Disease and Deep Brain Stimulation
This study is looking at how deep brain stimulation helps people with Parkinson's disease by checking the brain's electrical activity, and if you join in, you could help us understand how to make this treatment even better for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10802319 on NIH RePORTER |
What this research studies
This research investigates how deep brain stimulation (DBS) affects brain activity in patients with Parkinson's disease (PD) by analyzing voltage changes in the striatum, a key brain region involved in movement. By recording electrical signals from the brain during DBS treatment, the study aims to uncover the mechanisms behind its therapeutic effects. Patients may have the opportunity to contribute to this research by participating in recordings that help identify specific brain activity patterns associated with PD. The findings could lead to improved DBS techniques tailored to individual patient needs.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are considering or currently undergoing deep brain stimulation treatment.
Not a fit: Patients with other neurological conditions unrelated to Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the effectiveness of deep brain stimulation for patients with Parkinson's disease, potentially improving their quality of life.
How similar studies have performed: Previous studies have shown promise in using electrical activity patterns to improve deep brain stimulation outcomes, indicating that this approach could lead to significant advancements.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Han, Xue — Boston University (Charles River Campus)
- Study coordinator: Han, Xue
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.