Understanding brain activity patterns to improve treatment for schizophrenia
Examining the electroencephalographic fingerprint of default mode network hyperconnectivity for scalable and personalized neurofeedback in schizophrenia
['FUNDING_R21'] · NORTHEASTERN UNIVERSITY · NIH-10675554
This study is looking at how brain communication changes in people with schizophrenia who hear voices, and it will help them learn to control their brain activity through a safe and noninvasive method, which could help lessen their symptoms.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHEASTERN UNIVERSITY (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10675554 on ClinicalTrials.gov |
What this research studies
This research investigates how specific brain communication patterns are altered in individuals with schizophrenia, particularly those experiencing auditory hallucinations. By using advanced imaging techniques, the study aims to identify personalized brain activity profiles that can be targeted for treatment. Patients will engage in a noninvasive neurofeedback intervention, where they can learn to regulate their brain activity in real-time, potentially reducing their symptoms. The approach focuses on enhancing communication within brain networks to alleviate the distress caused by auditory hallucinations.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who experience auditory hallucinations related to schizophrenia.
Not a fit: Patients who do not have schizophrenia or do not experience auditory hallucinations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, personalized treatment option for individuals with schizophrenia who do not respond to traditional medications.
How similar studies have performed: Other research has shown promising results using neurofeedback techniques for various mental health conditions, suggesting potential for success in this novel application.
Where this research is happening
BOSTON, UNITED STATES
- NORTHEASTERN UNIVERSITY — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAUER HOSS, CLEMENS CHRISTIAN CHIMALPOPOCA — NORTHEASTERN UNIVERSITY
- Study coordinator: BAUER HOSS, CLEMENS CHRISTIAN CHIMALPOPOCA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder