Understanding brain activity patterns for personalized neurofeedback treatment

Investigating electroencephalographic predictors of default mode network anticorrelation for personalized neurofeedback

NIH-funded research Drexel University · NIH-10612484

This study is exploring how we can use brain activity measurements to create personalized tools that help people with mental health conditions learn to manage their own brain activity, making it easier and more effective for them to improve their mental well-being.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionDrexel University NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10612484 on NIH RePORTER

What this research studies

This research investigates how brain activity, measured through electroencephalography (EEG), can be used to create personalized neurofeedback systems for individuals with neuropsychiatric conditions. By mapping brain network interactions, the study aims to identify specific targets for treatment that can help patients learn to regulate their own brain activity. The approach seeks to make neurofeedback more accessible and effective by using EEG instead of more complex and expensive imaging techniques like fMRI. Patients will be able to engage in real-time feedback to improve their mental health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing neuropsychiatric conditions such as depression or other mental health disorders.

Not a fit: Patients with neurological conditions that are not primarily psychiatric or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for mental health disorders, improving patients' quality of life.

How similar studies have performed: Previous research has shown promise in using neurofeedback for mental health treatment, but this specific approach using EEG as a substitute for fMRI is relatively novel.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.