Understanding biological changes in cells and tissues using advanced technologies
Official title: BIOPSII Core
Funded at University of Michigan at Ann Arbor · NIH-11009437 · Data updated 2026-11-12
This study is exploring how individual cells change in people with skin and systemic lupus, using advanced technology to help us better understand these conditions and potentially improve treatments for patients.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | June 5, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $350,816 |
| NIH project number | 1P01AI179251-01A1 |
| Project ID | NIH-11009437 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals diagnosed with cutaneous lupus erythematosus or systemic lupus erythematosus.
✕Less likely to help
Patients with conditions unrelated to lupus or those not diagnosed with any autoimmune diseases may not benefit from this research.
What this research studies
This research focuses on utilizing cutting-edge single-cell and spatial technologies to measure biological changes at the individual cell level. By integrating various data types, including gene expression and epigenetic regulation, the project aims to provide detailed insights into disease processes. The BIOPSII core will support research efforts related to cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) by developing standardized data processing and analysis pipelines. Patients may benefit from improved understanding and treatment options for these conditions.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnostics and targeted therapies for patients with lupus-related conditions.
How similar studies have gone: Previous research utilizing single-cell and spatial technologies has shown promising results in understanding complex diseases, indicating a strong potential for success in this approach.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Tsoi, Lam Cheung — University of Michigan at Ann Arbor
- Study coordinator: Tsoi, Lam Cheung
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.