Understanding biological changes in cells and tissues using advanced technologies
BIOPSII Core
This study is exploring how individual cells change in people with skin and systemic lupus, using advanced technology to help us better understand these conditions and potentially improve treatments for patients.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11009437 on NIH RePORTER |
What this research studies
This research focuses on utilizing cutting-edge single-cell and spatial technologies to measure biological changes at the individual cell level. By integrating various data types, including gene expression and epigenetic regulation, the project aims to provide detailed insights into disease processes. The BIOPSII core will support research efforts related to cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) by developing standardized data processing and analysis pipelines. Patients may benefit from improved understanding and treatment options for these conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with cutaneous lupus erythematosus or systemic lupus erythematosus.
Not a fit: Patients with conditions unrelated to lupus or those not diagnosed with any autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnostics and targeted therapies for patients with lupus-related conditions.
How similar studies have performed: Previous research utilizing single-cell and spatial technologies has shown promising results in understanding complex diseases, indicating a strong potential for success in this approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Tsoi, Lam Cheung — University of Michigan at Ann Arbor
- Study coordinator: Tsoi, Lam Cheung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.