Understanding barriers to using new Alzheimer's therapies for older adults
Official title: Cost and Non-Cost Barriers to Use of Novel AD Therapeutics among Older Adults
Funded at University of Southern California · NIH-11537515 · Data updated 2026-11-12
This project studies what stops people 21 and older at risk for Alzheimer's from using new therapies and how those barriers affect health, daily life, and costs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $554,493 |
| NIH project number | 4R33AG089049-03 |
| Project ID | NIH-11537515 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older at elevated risk for Alzheimer's disease or living with Alzheimer's-related dementia, and their caregivers.
✕Less likely to help
People not considering or eligible for novel Alzheimer's therapies or those without access barriers may see limited direct benefit.
What this research studies
If funded, researchers will explore real-world factors that prevent or delay older adults from taking new Alzheimer's medicines, including costs, insurance coverage, and access. The team will build on prior interviews and surveys to examine how these barriers influence health outcomes and quality of life, and they will assess prevention options in addition to disease-modifying therapies. The project uses interviews, surveys, and population data to identify practical ways to improve uptake and affordability for patients and caregivers.
Why it matters
Potential benefit: If successful, the work could lead to clearer pathways for older adults to access effective Alzheimer's therapies and improved guidance for insurers and clinicians.
How similar studies have gone: Previous qualitative interviews and surveys helped shape understanding of barriers; this project expands on that work with larger, diverse populations.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Jacobson, Mireille — University of Southern California
- Study coordinator: Jacobson, Mireille
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.