Understanding atherosclerosis and its effects on the body
PPG Phenotyping
This study is looking at how atherosclerosis affects the heart and other parts of the body, and it needs volunteers to help by providing blood samples so researchers can better understand the disease and its progression.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10908529 on NIH RePORTER |
What this research studies
This research focuses on the detailed analysis of atherosclerosis and related cardiovascular conditions through standardized methodologies. It involves phenotyping both human subjects and mouse models to gather insights into the disease's progression and its impact on various body tissues. The project includes multiple specialized sub-cores that analyze liver histology, lipid levels, and cytokine profiles, providing a comprehensive understanding of the disease mechanisms. Patients may be involved in providing blood plasma samples and other biological materials to support these analyses.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals diagnosed with atherosclerosis or related cardiovascular conditions.
Not a fit: Patients without cardiovascular conditions or those not willing to provide biological samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for patients with atherosclerosis and cardiovascular diseases.
How similar studies have performed: Previous research has shown success in using similar phenotyping approaches to understand cardiovascular diseases, indicating a promising avenue for this project.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Witztum, Joseph L. — University of California, San Diego
- Study coordinator: Witztum, Joseph L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.