Understanding anxiety in people recovering from alcohol use disorder
Neural mechanisms of anxiety during early and protracted abstinence in alcohol use disorder
['FUNDING_OTHER'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10663519
This study is looking at how the brain reacts to anxiety when people with alcohol use disorder stop drinking, and it hopes to find new ways to help those in recovery feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10663519 on ClinicalTrials.gov |
What this research studies
This research investigates the brain mechanisms that contribute to anxiety during periods of abstinence from alcohol in individuals with alcohol use disorder (AUD). By using advanced imaging techniques like functional MRI, the study aims to identify specific brain areas involved in anxiety, which could lead to new treatment options. The principal investigator, Dr. Srivastava, will receive training in clinical trials and addiction neuroscience to ensure a thorough understanding of the issues at hand. The ultimate goal is to uncover how changes in brain circuitry affect anxiety levels, which may help in developing targeted therapies for those in recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with alcohol use disorder who are currently in abstinence or considering abstinence.
Not a fit: Patients who are actively using alcohol or have not been diagnosed with alcohol use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that reduce anxiety and improve recovery outcomes for individuals with alcohol use disorder.
How similar studies have performed: Previous research has shown promise in understanding the neural mechanisms of anxiety in addiction, suggesting that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SRIVASTAVA, A B — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: SRIVASTAVA, A B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Chronic Disease