Understanding and treating fibrosis in various diseases
Center for Quantitative Biology: a focus on “omics”, from organisms to single cells Supplement 4
['FUNDING_OTHER'] · DARTMOUTH COLLEGE · NIH-11047270
This study is exploring how fibrosis, which causes unwanted scarring in tissues, happens in conditions like autoimmune diseases and cancer, and it's working on new treatments to help people with systemic sclerosis and similar issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DARTMOUTH COLLEGE (nih funded) |
| Locations | 1 site (HANOVER, UNITED STATES) |
| Trial ID | NIH-11047270 on ClinicalTrials.gov |
What this research studies
This research focuses on the mechanisms behind fibrosis, a condition that can arise from chronic inflammation, autoimmune diseases, and cancer. The team aims to uncover the cellular and molecular interactions that lead to excessive tissue scarring and develop new therapies to reverse this process. By utilizing advanced bioinformatics and cellular immunotherapy, they hope to create effective treatments for conditions like systemic sclerosis, which currently lacks validated therapies. The research involves interdisciplinary collaboration to assess the efficacy of these novel approaches in real-world settings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic inflammatory conditions, autoimmune diseases, or cancers associated with fibrosis.
Not a fit: Patients with conditions unrelated to fibrosis or those who do not have chronic inflammatory or autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively treat or even reverse fibrosis, improving outcomes for patients with chronic diseases.
How similar studies have performed: Previous research has shown promise in reversing fibrosis, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
HANOVER, UNITED STATES
- DARTMOUTH COLLEGE — HANOVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WHITFIELD, MICHAEL L — DARTMOUTH COLLEGE
- Study coordinator: WHITFIELD, MICHAEL L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases