Understanding and measuring negative symptoms in schizophrenia

Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation Study

NIH-funded research University of Georgia · NIH-10528461

This study is looking to create better ways to identify feelings like low motivation and emotional flatness in young adults who might be at risk for schizophrenia, so that they can get the right help and support they need.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Georgia NIH-funded
Lab location1 site (Athens, United States)
Project IDNIH-10528461 on NIH RePORTER

What this research studies

This research focuses on developing and validating new assessment tools for negative symptoms associated with schizophrenia, particularly in young adults at risk of developing psychosis. It aims to enhance the detection of these symptoms, which include a lack of motivation and emotional expression, to improve treatment outcomes. By addressing the limitations of existing assessment scales, the study seeks to provide a more accurate understanding of negative symptoms in this vulnerable population. Participants will be involved in assessments that could lead to better-targeted interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults who are at ultra-high risk for developing psychosis and exhibit negative symptoms.

Not a fit: Patients who do not exhibit negative symptoms or are not at risk for developing psychosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved detection and treatment of negative symptoms in young adults at risk for schizophrenia, enhancing their quality of life.

How similar studies have performed: Previous research has shown that developing targeted assessment tools can significantly improve the understanding and treatment of psychiatric conditions, indicating potential success for this approach.

Where this research is happening

Athens, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.