Understanding and improving risk assessment in familial hypercholesterolemia
Improving Risk Stratification in Familial Hypercholesterolemia (RISK-FH)
This study is looking at familial hypercholesterolemia (FH), a genetic condition that causes high cholesterol and heart disease risk, to better understand its different types and how they affect heart health, so doctors can give clearer advice to patients from all backgrounds.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Geisinger Clinic NIH-funded |
| Lab location | 1 site (Danville, United States) |
| Project ID | NIH-10872313 on NIH RePORTER |
What this research studies
This research investigates familial hypercholesterolemia (FH), a genetic condition that leads to high cholesterol and increases the risk of heart disease. It aims to identify different subtypes of FH and how they affect the risk of cardiovascular disease. By analyzing genetic factors, cholesterol levels, and other health indicators, the study seeks to develop better methods for assessing risk in patients with FH. The findings could help healthcare providers communicate risks more effectively to patients from diverse backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with familial hypercholesterolemia or those with a family history of high cholesterol and early heart disease.
Not a fit: Patients without a diagnosis of familial hypercholesterolemia or those who do not have a family history of related cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate risk assessments and improved treatment strategies for patients with familial hypercholesterolemia.
How similar studies have performed: Previous research has shown promise in improving risk assessment for cardiovascular diseases through genetic and phenotypic analysis, indicating that this approach may yield valuable insights.
Where this research is happening
Danville, United States
- Geisinger Clinic — Danville, United States (Active)
Researchers
- Principal investigator: Oetjens, Matthew — Geisinger Clinic
- Study coordinator: Oetjens, Matthew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.