Unconscious brain training to reduce animal phobias

Unconscious reduction of fear through decoded neuro-reinforcement

NIH-funded research University of California Los Angeles · NIH-11284025

This approach uses unconscious brain feedback during MRI to reduce fear of animals in people with specific animal phobias.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11284025 on NIH RePORTER

What this research studies

You would come to UCLA for MRI sessions where researchers decode brain patterns tied to images of feared animals and then reinforce those patterns without you consciously seeing the images. The procedure uses neuro-reinforcement to lower fear-related activity in the amygdala while you remain unaware of the specific content being targeted. The trial is double-blind and placebo-controlled, and researchers will track changes in attention to animals, avoidance behavior, and physiological fear responses over time. If eligible, you would attend several visits over weeks to months and complete behavioral tests before and after the intervention.

Who could benefit from this research

Good fit: Adults with a diagnosed specific phobia of animals (for example spiders or birds) who can safely undergo MRI and who have difficulty tolerating exposure therapy are ideal candidates.

Not a fit: People without animal-specific phobias, those with contraindications to MRI (e.g., certain implants or severe claustrophobia), or those whose primary issues are other psychiatric conditions may not benefit.

Why it matters

Potential benefit: If successful, this could lower animal-related fear and avoidance without the distress of traditional exposure therapy.

How similar studies have performed: Early pilot data from the team showed promising reductions in fear using this unconscious neuro-reinforcement approach, but larger controlled trials are still needed.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.