Transforming scar tissue into healing skin
Converting wound scar into healing with regeneration
This study is looking at how a special pathway in our bodies can help heal skin wounds better and reduce scarring, which could be great news for anyone dealing with skin injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10793563 on NIH RePORTER |
What this research studies
This research investigates how a specific signaling pathway, known as SHH, can enhance the healing process of skin wounds in mammals, including humans. Typically, when skin is injured, it heals with scar tissue that lacks the original skin structure, including hair follicles. The researchers aim to determine if activating SHH can help regenerate these lost structures by studying the role of certain cells in the healing process. By understanding these mechanisms, the research hopes to find ways to improve skin regeneration and reduce scarring.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with skin injuries or scars, particularly those resulting from skin cancer or other malignant skin conditions.
Not a fit: Patients with non-skin-related injuries or conditions that do not involve skin healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance skin healing and reduce scarring for patients with skin injuries.
How similar studies have performed: Other research has shown promise in using signaling pathways to enhance tissue regeneration, suggesting that this approach could be effective.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Ito, Mayumi — New York University School of Medicine
- Study coordinator: Ito, Mayumi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.