NIH-funded research NIH-funded research

Trajectories of secondary outcomes in CTN trials

Official title: Western States Node of the National Drug Abuse Treatment Clinical Trials Network (CTN-0149)

Funded at Oregon Health & Science University · NIH-11523829 · Data updated 2026-11-12

Researchers at BU and collaborators will analyze existing CTN trial data to find patterns in mental health and substance use outcomes over time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startMarch 1, 2026
Project endFebruary 28, 2027
Funding year2026
Award (this year)$89,999
NIH project number3UG1DA015815-25S1
Project IDNIH-11523829 on NIH RePORTER

Who could benefit from this research

Could help

Individuals enrolled in CTN trials or similar substance use and mental health treatment studies who contributed data and may benefit from subgroup-informed care.

Less likely to help

Patients not represented in CTN datasets or those not receiving evidence-based treatment may not see direct benefits.

What this research studies

This project uses CTN trial data to identify subgroups of participants based on how their mental health and substance use change over time. The team will develop and implement a protocol, decide which CTN studies to include, and create an analysis plan to uncover meaningful patterns. Results will help clinicians tailor interventions to patient subgroups and improve future trial designs.

Why it matters

Potential benefit: Could help patients receive more personalized care by identifying which treatment patterns work best for different groups.

How similar studies have gone: Previous analyses of longitudinal CTN data have identified clinically relevant subgroups and guided treatment approaches, though this project focuses on secondary outcomes across multiple trials.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Korthuis, Philip Todd — Oregon Health & Science University
  • Study coordinator: Korthuis, Philip Todd

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.