Trait-Based Metagenomics to Understand Microbiome Dynamics in Cancer Care
Official title: Trait-Based Metagenomics for Predicting Microbiome Dynamics
Funded at State University New York Stony Brook · NIH-11426858 · Data updated 2026-11-12
A cancer-focused grant is funding new software and methods to understand how complex gut microbiomes behave and affect treatment outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $396,667 |
| NIH project number | 1R35GM165706-01 |
| Project ID | NIH-11426858 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients undergoing cancer treatment who are willing to contribute gut microbiome samples and related health data.
✕Less likely to help
Individuals not participating in microbiome sampling or without cancer therapy plans may not directly benefit.
What this research studies
This project aims to move beyond just listing gut microbes by focusing on the traits and functions that drive microbiome behavior. Researchers will develop and apply advanced bioinformatics tools to connect microbial traits with community dynamics in the human gut, with the ultimate goal of informing cancer treatment strategies. The work will involve integrating genomic information with models of how microbial communities grow and interact, to better predict how microbiomes influence health during cancer therapy.
Why it matters
Potential benefit: If successful, the project could lead to better prediction of how gut microbes affect cancer treatment and potentially guide personalized therapies.
How similar studies have gone: Similar approaches have shown that microbiome traits can influence health outcomes, but linking complex traits to clinical results remains challenging.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Weissman, Jackie Lee — State University New York Stony Brook
- Study coordinator: Weissman, Jackie Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.