Training to improve emotional regulation in patients with Borderline Personality Disorder

Cognitive Reappraisal Training Targeting Emotion Circuits As a Therapeutic Intervention in Borderline Patients

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10718246

This study is testing a new training program to help people with Borderline Personality Disorder learn better ways to manage their emotions, aiming to reduce mood swings and improve how they respond to feelings and social situations.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10718246 on NIH RePORTER

What this research studies

This research focuses on developing a training program aimed at enhancing cognitive reappraisal skills in individuals with Borderline Personality Disorder (BPD). By teaching patients how to better regulate their emotions through specific cognitive strategies, the study seeks to address the extreme mood swings and emotional instability that characterize BPD. Participants will engage in a structured training program that targets the brain's emotion circuits, with the goal of improving their emotional responses to social and emotional events. The effectiveness of this intervention will be assessed using advanced neuroimaging techniques to observe changes in brain activity related to emotional processing.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Borderline Personality Disorder who experience significant emotional instability.

Not a fit: Patients who do not have a diagnosis of Borderline Personality Disorder or those with severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective therapeutic interventions for individuals suffering from Borderline Personality Disorder, potentially reducing symptoms and improving quality of life.

How similar studies have performed: Previous research has shown promise in using cognitive reappraisal techniques to improve emotional regulation, suggesting that this approach may be effective for treating BPD.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Borderline Personality Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.