Tracking Viruses in 3D to Understand Infections
Unraveling the Viral Infection Pathway with Virus-locked Observation
['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-11120871
This research uses a new 3D tracking method to watch how viruses infect cells deep within tissues, like those in the lungs or gut.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11120871 on ClinicalTrials.gov |
What this research studies
We are developing a powerful new microscopy technique called 3D Tracking and Imaging (3D-TrIm) that lets us follow individual viruses in real-time. This method allows us to see how viruses move and interact with cells in complex environments, similar to how they behave inside the body. By looking beyond simple lab dishes, we can better understand the critical steps viruses take to infect tissues like the lining of your lungs or digestive system. This deeper understanding of viral behavior could help us find new ways to stop infections.
Who could benefit from this research
Good fit: This is fundamental laboratory research, so there are no direct patient participation opportunities at this time, but future clinical applications could benefit patients with viral infections.
Not a fit: Patients seeking immediate treatment or direct participation in a clinical trial will not find direct benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of how viruses infect the body, which might help develop new ways to prevent or treat viral illnesses.
How similar studies have performed: While single virus tracking methods have provided insights, this specific 3D tracking and imaging technique is a novel approach designed to overcome limitations of previous methods.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WELSHER, KEVIN — DUKE UNIVERSITY
- Study coordinator: WELSHER, KEVIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections