Tracking live cells and their genetic information using laser technology
Official title: Laser particles-based spatiotemporal and dynamic single-cell multiomics
Funded at Massachusetts General Hospital · NIH-10897238 · Data updated 2026-11-12
This study is testing a new technology that uses lasers to watch live cells and gather important genetic information about them, which could help doctors better understand and treat breast cancer.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $136,110 |
| NIH project number | 5K99HG013129-02 |
| Project ID | NIH-10897238 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with breast cancer who are interested in innovative treatment approaches.
✕Less likely to help
Patients with conditions unrelated to cancer or those who are not diagnosed with any cellular abnormalities may not benefit from this research.
What this research studies
This research focuses on developing a new technology that uses laser particles to track live cells while collecting detailed genetic and molecular information from them. By employing a unique barcoding system, researchers aim to observe how cells behave in real-time and gather their genomic data simultaneously. This approach allows for a comprehensive understanding of cellular dynamics and interactions, which is crucial for advancing cancer biology, particularly in breast cancer. Patients may benefit from insights gained through this innovative method, which could lead to improved diagnostic and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to more precise and personalized treatment options for patients with breast cancer.
How similar studies have gone: Similar research approaches have shown promise in advancing our understanding of cellular behavior and molecular interactions, indicating a strong potential for success in this novel application.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Wu, Yue Jane — Massachusetts General Hospital
- Study coordinator: Wu, Yue Jane
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.