Tracking drug-resistant bacteria in low-resource areas
Official title: Surveillance of drug-resistant bacteria in resource-limited settings: a focus on cost-effective long-read sequencing of eyedrop-associated P. aeruginosa and locally sourced metagenomic samples
Funded at California State University Fresno · NIH-10937544 · Data updated 2026-11-12
This study is looking at how to better track drug-resistant bacteria in eyedrops, especially in places that don't have a lot of resources, so that patients can get faster and more accurate help for infections caused by these tough germs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State University Fresno NIH-funded |
| Lab location | 1 site (Fresno, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $175,000 |
| NIH project number | 1R16AI184350-01 |
| Project ID | NIH-10937544 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living in resource-limited settings who are at risk of infections caused by drug-resistant bacteria.
✕Less likely to help
Patients who are not in resource-limited areas or those not affected by drug-resistant infections may not benefit from this research.
What this research studies
This research focuses on monitoring drug-resistant bacteria, particularly Pseudomonas aeruginosa found in eyedrops, in resource-limited settings. It aims to establish a decentralized surveillance system that utilizes cost-effective long-read sequencing technology to detect and analyze these bacteria and their associated bacteriophages. By employing affordable sequencing methods, the project seeks to improve the accuracy and efficiency of identifying drug-resistant infections, which can help in managing outbreaks more effectively. Patients in these communities may benefit from enhanced monitoring and quicker responses to infections caused by superbugs.
Why it matters
Potential benefit: If successful, this research could lead to improved detection and management of drug-resistant infections, ultimately saving lives and reducing healthcare costs.
How similar studies have gone: Previous research has shown success in using decentralized surveillance systems for monitoring antimicrobial resistance, indicating that this approach has potential.
Where this research is happening
-
California State University Fresno
Fresno, United States Active
Researchers
- Principal investigator: Shim, Hyunjin — California State University Fresno
- Study coordinator: Shim, Hyunjin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.